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Bristol-Myers Squibb reveals gender-based HIV drug data
06 Aug 2008
Clinical Research
Bristol-Myers Squibb says trial data has shown that its HIV drug Reyataz achieved similar levels of success in men and women.
The study, which involved 277 women and 606 men from 29 countries, tested the efficacy of the drug when used as part of a once-daily combination therapy with ritonavir, in comparison with a twice-daily lopinavir and ritonavir formulation.
Overall, it found 78 per cent of the 440 patients in the Reyataz group and 76 per cent of the 443 patients in the lopinavir group achieved an undetectable viral load at 48 weeks.
Within the Reyataz arm, 76 per cent of women achieved the undetectable viral load, compared with 79 per cent of men.
Dawn Averitt Bridge, founder and chair of the board at the Well Project, said: "It is very important for women to be involved in clinical research so we can better understand efficacy and tolerability of antiretroviral therapy in women."
She suggested that the study had "made a significant contribution to that understanding".
Bristol-Myers Squibb was in the news last week when it tabled an offer to acquire ImClone Systems at a price of $60.00 (£30.68) per share.
