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High-dose flu vaccine 'offers greater protection'

30 Oct 2008

Clinical Research

An investigational high-dose influenza vaccine has been shown to provide greater levels of protection than the standard flu jab in older age groups, it is claimed.

The high-dose vaccine increased immune responses to all three influenza strains compared to the standard medicine, Sanofi-aventis says.

Almost 4,000 people aged 65 or over took part in the phase-three study.

"Development of an influenza vaccine that will provide an improved immune response in older adults is important because this population has the highest rates of complications from influenza, including hospitalisation and death," comments Ann Falsey, associate professor of medicine at the University of Rochester in New York.

Meanwhile, drugs giant Wyeth has said it has developed a novel vaccine which could provide increased protection against pneumococcal disease.

According to the firm, data from clinical studies suggests its investigational 13-valent pneumococcal conjugate vaccine may offer broader protection from the condition in infants and young children compared to the seven-valent vaccine Prevnar.


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